Semaglutide cost comparison chart showing brand-name vs compounded pricing without insurance
on October 31, 2025

How Much Does Semaglutide Cost Without Insurance?

Last Updated: 2025-10-30

Quick Answer: Semaglutide costs between $200-$1,500 per month without insurance, depending on whether you choose brand-name (Wegovy/Ozempic) or compounded semaglutide. Compounded options typically range from $200-$400/month, while brand-name versions cost $900-$1,500/month at retail prices.

Understanding the true cost of semaglutide for weight loss can be overwhelming. While this groundbreaking GLP-1 medication has proven highly effective for weight management, navigating pricing without insurance coverage requires careful consideration of your options. In this comprehensive guide, we'll break down exactly what you'll pay for different semaglutide options and help you find the most affordable path to your weight loss goals.

Understanding Semaglutide Pricing: Brand vs. Compounded

The cost of semaglutide varies dramatically based on which version you choose. Let's explore the two main categories:

Brand-Name Semaglutide (Wegovy & Ozempic)

Brand-name semaglutide medications come with premium pricing:

  • Wegovy (FDA-approved for weight loss): $1,349-$1,595 per month at retail pharmacies

Source: FDA Press Release

  • Ozempic (FDA-approved for Type 2 diabetes, used off-label for weight loss): $968-$1,200 per month
  • Both require ongoing monthly costs as long as you continue treatment
  • Most health insurance plans don't cover these medications for weight loss without comorbidities

For a comprehensive overview of how semaglutide works and its benefits, see our complete guide to semaglutide.

Compounded Semaglutide

Compounded semaglutide offers the same active ingredient at a fraction of the brand-name cost:

  • Typical cost range: $200-$400 per month
  • Same active ingredient (semaglutide) as brand-name options
  • Created by FDA-registered 503B compounding pharmacies
  • Often includes medical supervision and support

Many patients wonder about compounded semaglutide safety compared to brand-name versions. When sourced from reputable 503B facilities, compounded semaglutide maintains the same quality standards and effectiveness.

Cost Breakdown by Provider Type

Where you obtain semaglutide significantly impacts your total cost. Here's what to expect from different provider types:

1. Telehealth Weight Loss Companies ($200-$400/month)

What's Included:

  • Compounded semaglutide medication
  • Virtual doctor consultation
  • Ongoing medical monitoring
  • Medication shipped to your door
  • Customer support

Examples:

  • Contour Health: Starting at $179/month with medical supervision included (learn more)
  • Other telehealth providers: $250-$400/month

Pros: Convenient, all-inclusive pricing, medical oversight included
Cons: May not accept insurance (though often cheaper than copays)

2. Traditional Doctor + Retail Pharmacy ($900-$1,500/month)

Costs Include:

  • Initial doctor visit: $150-$300
  • Follow-up appointments: $100-$200 each
  • Brand-name medication: $900-$1,500/month
  • Lab work: $100-$500 (if needed)

Total Monthly Cost: $1,000-$1,800+ for first month, $900-$1,500 ongoing

Pros: Established relationship with your doctor, potential insurance coverage
Cons: Significantly more expensive without insurance, requires in-person visits

3. Compounding Pharmacy Only ($200-$450/month)

If you have a prescription from your doctor:

  • Compounded semaglutide: $200-$400/month
  • Doctor visits billed separately: $100-$300 per visit
  • You coordinate everything yourself

Pros: Work with your existing doctor, somewhat lower medication cost
Cons: More coordination required, separate bills for medical care

How Dosing Affects Monthly Costs

Your semaglutide weight loss timeline includes a gradual dose escalation that can impact your monthly costs:

Standard Dosing Schedule:

Month Weekly Dose Notes on Cost
Month 1 0.25 mg Lower starter dose may cost less with some providers
Month 2 0.5 mg Gradual increase
Month 3 1.0 mg Most patients see significant results at this dose
Month 4+ 1.7-2.4 mg Maintenance dose, steady monthly cost

Some providers offer tiered pricing based on dosage, while others charge a flat monthly rate regardless of dose. At Contour Health, our pricing includes all dosages, eliminating surprise cost increases as you progress.

Hidden Costs to Consider

Beyond the medication itself, factor in these additional expenses:

Required Medical Monitoring

  • Initial consultation: $0-$300 (often included with telehealth)
  • Follow-up visits: $0-$200/month (frequency varies by provider)
  • Lab work: $100-$500 (baseline and periodic testing)

Injection Supplies

  • Syringes/needles: Usually included, but verify with your provider
  • Alcohol swabs: ~$5-10 (if not included)
  • Sharps container: ~$10-20 (one-time purchase)

Pro Tip: Most reputable providers include all injection supplies. If considering a provider that charges extra, factor this into your total cost comparison.

Managing Side Effects

Some patients need support managing semaglutide side effects, which may include:

  • Anti-nausea medication: $10-50/month (if needed)
  • Dietary supplements: $20-50/month (optional)
  • Additional medical consultations: $100-200 (if complications arise)

Most patients don't need additional medications, but it's wise to budget for potential needs, especially in the first 2-3 months as your body adjusts.

5 Ways to Lower Your Semaglutide Costs

1. Choose Compounded Over Brand-Name

The most impactful way to reduce costs is opting for compounded semaglutide. You'll save $600-$1,100 per month compared to Wegovy, receiving the same active ingredient from FDA-registered facilities.

2. Use Telehealth Services

Telehealth providers typically offer all-inclusive pricing that's more affordable than traditional healthcare:

  • No separate doctor visit fees
  • Free medication shipping
  • Unlimited messaging with medical team
  • All supplies included

3. Compare Oral vs. Injectable Options

For those concerned about injections, oral semaglutide options are available. While pricing varies, some patients find oral administration more convenient. Contour Health offers both oral and injectable semaglutide, allowing you to choose what works best for your lifestyle.

4. Check Manufacturer Savings Programs

If you prefer brand-name options:

  • Novo Nordisk Savings Card: May reduce Wegovy to $0-$500/month for eligible patients
  • Eligibility requirements: Commercial insurance, meet BMI criteria, other restrictions apply
  • Note: Not available for Medicare/Medicaid patients or uninsured individuals

5. Consider Alternative GLP-1 Medications

If semaglutide costs remain prohibitive, explore other GLP-1 options:

What About Insurance Coverage?

Insurance coverage for semaglutide without a diabetes diagnosis is complex:

When Insurance Might Cover Semaglutide:

  • BMI ≥27 with weight-related comorbidity (hypertension, type 2 diabetes, sleep apnea, etc.)
  • BMI ≥30 without comorbidities
  • Prior authorization approved by your doctor
  • Documented weight loss attempts

Why Insurance Often Denies Coverage:

  • Weight loss medications excluded from formulary
  • Plan classifies it as "cosmetic" rather than medical necessity
  • Prior authorization requirements not met
  • Tier 4 or specialty medication with 30-50% coinsurance

Reality Check: Even with insurance coverage, your copay may be $300-$500/month for brand-name semaglutide, making compounded options from telehealth providers financially comparable or cheaper.

Long-Term Cost Considerations

How Long Will You Need Semaglutide?

Most patients take semaglutide for 12-24 months to reach their goal weight, with some continuing for maintenance:

Duration Compounded Cost Brand-Name Cost Savings with Compounded
6 months $1,800-$2,400 $5,400-$9,000 $3,600-$6,600
12 months $3,600-$4,800 $10,800-$18,000 $7,200-$13,200
24 months $7,200-$9,600 $21,600-$36,000 $14,400-$26,400

The long-term financial difference between compounded and brand-name semaglutide can be substantial, potentially saving $14,000-$26,000 over two years of treatment.

Maintenance Phase Considerations

After reaching your goal weight:

  • Some patients transition to lower maintenance doses, potentially reducing costs
  • Others discontinue medication and maintain results through lifestyle changes
  • Many continue at their therapeutic dose long-term to prevent weight regain

Discuss your maintenance plan with your healthcare provider to budget appropriately for the long term.

The Value Equation: Cost vs. Results

When evaluating semaglutide costs, consider the potential return on investment:

Average Weight Loss Results:

  • Clinical trials: 15-20% total body weight loss over 68 weeks

Source: New England Journal of Medicine

  • Real-world results: 10-15% body weight reduction common
  • Example: 200 lb person loses 20-40 lbs on average

Health Benefits Beyond Weight Loss:

  • Improved cardiovascular health

Source: American Heart Association

  • Better blood sugar control
  • Reduced inflammation
  • Lower risk of obesity-related complications

Cost Per Pound Lost:

Using compounded semaglutide at $300/month for 12 months:

  • Total investment: $3,600
  • Average weight loss: 30 lbs (for 200 lb person)
  • Cost per pound: $120

Compare this to:

  • Medical weight loss programs: $150-200/lb
  • Weight loss surgery: $200-$1,000/lb (before complications)
  • Long-term gym/trainer/nutritionist: $100-300/lb

Transparent Pricing at Contour Health

At Contour Health, we believe in straightforward, affordable pricing for weight loss medication:

What You Get:

  • Compounded semaglutide (all doses included)
  • Complete medical evaluation
  • Ongoing physician supervision
  • Unlimited messaging with medical team
  • All injection supplies included
  • Free shipping
  • Cancel anytime, no long-term commitment

Pricing: Starting at $179/month

Explore our semaglutide program →

We also offer oral semaglutide for those who prefer not to use injections, and compounded tirzepatide as an alternative GLP-1 medication option.

Making Your Decision

Choosing the right semaglutide option comes down to balancing cost, convenience, and quality:

Choose Compounded Semaglutide If:

  • You're paying out-of-pocket without insurance coverage
  • Your insurance copay exceeds $300/month
  • You value convenience and all-inclusive pricing
  • You want medical supervision without multiple doctor visits
  • You're comfortable with telehealth

Choose Brand-Name If:

  • Your insurance fully covers the medication
  • Your copay is under $100/month
  • You prefer working exclusively with in-person doctors
  • You have concerns about compounded medications

Questions to Ask Any Provider:

  1. What's the total monthly cost, including all fees?
  2. Are medical consultations and monitoring included?
  3. What supplies are provided?
  4. Can I cancel anytime without penalties?
  5. What support is available if I experience side effects?
  6. Is this price guaranteed, or will it increase with higher doses?
  7. What is your compounding pharmacy's accreditation?

The Bottom Line

Semaglutide costs without insurance range dramatically from $200 to $1,500 per month, with compounded options offering significant savings without sacrificing quality or effectiveness. For most patients paying out-of-pocket, compounded semaglutide from reputable telehealth providers delivers the best value: affordable pricing, medical oversight, and convenient access to this life-changing medication.

The key is choosing a provider you trust who offers transparent pricing, genuine medical supervision, and high-quality compounded medication from FDA-registered facilities. Don't let cost prevent you from accessing effective weight loss treatment—affordable options exist that can fit within your budget while supporting your health goals.

Ready to get started? Learn more about our affordable semaglutide program at Contour Health, where transparent pricing meets quality medical care.

Medical Disclaimer

This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or qualified healthcare provider with any questions about a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this website.